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Blood proteins that may predict cancer 7 years earlier identified

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New Delhi, May 15 (IANS) UK scientists have identified blood proteins linked to 19 different types of cancer, which could predict the deadly disease at least seven years before diagnosis.

The scientists from the Oxford Population Health in the UK identified 618 proteins, including 107 proteins in a group of people whose blood was collected at least seven years before diagnosis.

“These proteins could be involved at the very earliest stages of cancer, where it could be prevented,” they said in the studies published in the journal Nature Communications on Wednesday.

To find the proteins, the scientist deployed a powerful technique called proteomics, which helps analyse a large set of proteins in tissue samples at a single point in time. This helps to see how the proteins interact with each other and find any important differences between tissue samples.

The first study analysed blood samples taken from more than 44,000 people, including over 4,900 people who subsequently had a cancer diagnosis.

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Proteomics helped scientists analyse a set of 1,463 proteins from a single sample of blood from each person.

The results showed 182 proteins that differed in the blood three years before a cancer diagnosis took place.

In the second study, genetic data from over 300,000 cancer cases were analysed.

The team found 40 proteins in the blood that determined a person’s risk of getting nine different types of cancer.

“The genes we are born with, and the proteins made from them, are hugely influential in how cancer starts and grows,” said Dr Joshua Atkins, Senior Genomic Epidemiologist at Oxford Population Health.

“This research brings us closer to being able to prevent cancer with targeted drugs — once thought impossible but now much more attainable,” added Dr Karl Smith-Byrne, Senior Molecular Epidemiologist at Oxford.

The team, however, called for further research to find out the exact role these proteins play in cancer development.

–IANS

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US FDA gives nod to Musk's Neuralink to implant brain chip in 2nd person

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New Delhi, May 20 (IANS) Tesla CEO Elon Musk-run brain-computer interface company Neuralink has reportedly received a nod from the US Food and Drug Administration (FDA) to implant its brain chip in a second person.

The approval for the second person to have a Neuralink chip came as the first recipient — Noland Armagh in the US — detailed his emotional journey.

The latest chip in the second recipient comes with some fixes, like embedding some of the device’s ultrathin wires deeper into the brain, The Wall Street Journal reported on Monday.

Musk or Neuralink were yet to officially react to the development.

The Neuralink chip can help restore full body control in people suffering from paralysis. The company earlier achieved a successful brain-chip implant with Armagh and began the applications for the second participant for the chip implant.

According to Musk, the company can bridge “severed nerve signals to a second Neuralink in the spine, restoring full body control”.

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With the chip in his brain, Arbaugh has enabled “telepathic control of a computer or phone just by thinking”. The Neuralink trials aim to assess the initial functionality of the wireless brain-computer interface for enabling people with paralysis to control external devices with their thoughts.

–IANS

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Delhi HC dismisses PIL seeking directions to medical professionals to reveal side effects of medicines

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New Delhi, May 20 (IANS) The Delhi High Court has dismissed a public interest litigation (PIL) seeking a direction to all medical professionals to provide an additional slip detailing possible risks and side effects associated with prescribed medicines.

A Bench, headed by Acting Chief Justice Manmohan, said that since the legislature, in its wisdom, has elected to impose this duty on the manufacturer and the pharmacist, it would “amount to judicial legislation” if a direction is issued as prayed for in the PIL.

“It is admitted that there is no (legal) vacuum, the directions prayed for cannot be issued. Accordingly, the present PIL along with applications is dismissed,” the bench, also comprising Justice Manmeet Pritam Singh Arora, ordered.

The PIL said that the patient has a right to make an informed choice and therefore, it should be mandatory for the doctor prescribing the drug to explain the side effects and possible risks attached to the prescribed drugs.

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It added that upon being made aware of the side effects of the drug being prescribed by the doctor, the patient would be able to make an informed choice, whether to consume it or not.

Referring to the existing regime, where the obligation to communicate the potential risks and side effects exists on the manufacturer and the pharmacists, the plea said that it is the medical practitioner prescribing the drug, who should be made responsible for handing out the information about the potential risk to the patient in the regional language.

In its response, the Union government stated that the Drugs and Cosmetics Act, 1945 and the Pharmacy Practice Regulations, 2015 already ensure that the risk is duly communicated to the patient, adding that the direction sought would hinder rather than facilitate medical advice to the patients.

–IANS

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178-yr-old practice of distributing ‘fish prasadam’ in Hyderabad to be on June 8-9

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Hyderabad, May 20 (IANS) Bathini family will distribute ‘fish prasadam’ to people suffering from asthma and other respiratory ailments here on June 8-9. The family announced on Monday that the annual event will begin at 11 a.m. on June 8 at Exhibitions Grounds, Nampally, and will continue till 11 a.m. on June 9.

Bathini Vishwanatham Goud, president, Bathini Mrigasira Trust, told media persons that they are making all arrangements for the distribution of fish prasadam.

Asthma patients from various parts of Telugu states and other places in the country take this prasadam in June every year in the hope of finding relief from respiratory problems.

The family requested concerned government departments to make arrangements like every year for the smooth conduct of the event.

This will be the first event after the death of the head of the family, Bathini Harinath Goud. He passed away at the age of 84 in June last year, following prolonged illness.

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He was the last of the fourth-generation Gouds distributing free fish medicine to asthma patients from across the country.

Harinath Goud was instrumental in organising the event for the last three decades after the demise of his elder brothers.

The Bathini Goud family claims to have been distributing this medicine free of cost for the last 178 years. The secret formula for the herbal medicine was given to their ancestor in 1845 by a saint after he took an oath that it would be administered free of cost.

Members of the Bathini Goud family administer the ‘wonder drug’ on ‘Mrigasira Karti’, (during the first week of June) which heralds the onset of the monsoon.

A yellow colour herbal paste prepared by the family is placed in the mouth of a live ‘murrel’ fingerling, which is then slipped through the throat of the patient. It is believed to provide much-needed relief if taken for three consecutive years. For vegetarians, the family gives medicine with jaggery.

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Asthma patients from various parts of the country flock to Hyderabad to take this treatment. However, the medicine lost its popularity during the last 15 years due to controversies pertaining to the contents of herbal paste.

Some groups working to inculcate scientific temper among people, termed the fish medicine a fraud. They also approached the court, claiming that since the herbal paste contains heavy metals, it can cause serious health problems.

However, Goud family claims that the tests in laboratories conducted as per court orders revealed that the herbal paste is safe.

After the challenge by the rationalists, the family started calling it ‘fish prasadam’.

Despite the controversies, people continue to throng the venue every year in hope of finding some relief to their nagging respiratory problems. However, the numbers have dwindled over the years.

–IANS

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18 per cent of teens drink caffeine to stay awake: Study

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New Delhi, May 20 (IANS) Among parents who said their teen drinks caffeine most or all the day of the week, a new study on Monday revealed that 18 per cent drink it to “stay awake”.

The study conducted by the US-based University of Michigan found that a quarter (25 per cent) of parents reported their teen consumes caffeine daily or nearly every day.

“Our report suggests parents may not always be aware of how much they should be limiting caffeine consumption for teens,” said poll co-director and Mott paediatrician Susan Woolford, MD.

The study is based on responses from 1,095 parents of teens polled in February.

Parents reported that the most common caffeine sources for their teen are soda (73 per cent), tea (32 per cent), coffee (31 per cent), and energy drinks (22 per cent) and said that they take caffeine most frequently at home (81 per cent), when dining out (43 per cent), with friends (3 per cent), and at school (25 per cent).

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“Caffeine is a drug that stimulates the brain and nervous system, and too much of it can contribute to a variety of health problems in young people,” Woolford said.

The American Academy of Pediatrics discourages caffeine intake by children and adolescents, and other experts suggest a limit of 100 milligrams per day for teens, the study mentioned.

About 60 per cent of parents said that they have heard about the risks of highly caffeinated products but roughly half mentioned that they rarely look at caffeine amounts when buying beverages for their teen.

“Parents should consider talking with their teen about the negative impact of excessive caffeine, and then explore non-caffeinated options they can try together at home, at school or when out with friends,” Woolford said.

“Parents may also enlist the teen’s healthcare provider in explaining the risks of caffeine and suggesting strategies to cut back,” she added.

–IANS

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Saudi king to undergo treatment for lung infection

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Riyadh, May 20 (IANS) The Saudi Royal Court has announced that Saudi King Salman bin Abdulaziz Al Saud will undergo treatment for a lung infection.

He underwent medical examinations on Sunday at the Royal Clinics of Al-Salam Palace in Jeddah due to high temperature and joint pain, Xinhua news agency reported.

The Saudi king was admitted to the King Faisal Specialist Hospital and Research Centre in Jeddah on April 24 for a routine health checkup.

–IANS

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